The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity.
Shefali ChaudharySimon ZhornitskyAlicia RoyChristine SummersTim AhlesChiang-Shan R LiHerta H ChaoPublished in: Cancer medicine (2022)
Six-month ADT affects hypothalamic functional connectivity with brain regions critical to cognitive motor and affective functions. Elevated hypothalamic MCC and PCG connectivity likely serve to functionally compensate for the effects of ADT and sustain attention and overall QoL. The longer-term effects of ADT remain to be investigated.
Keyphrases
- resting state
- functional connectivity
- working memory
- prostate cancer
- end stage renal disease
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- white matter
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- bipolar disorder
- multiple sclerosis
- mass spectrometry
- patient reported