5-Hydroxymethylcytosines in circulating cell-free DNA as a diagnostic biomarker for nasopharyngeal carcinoma.
Bijuan ChenDi WangYun XuQiaojuan GuoJianji PanSisi YuYunxiang FangShuxiang XiaoYuanyuan RuanShanshan YangMingan LinJinsheng HongZhouwei ZhanShaojun LinPublished in: European journal of cancer (Oxford, England : 1990) (2024)
5hmC modifications in cfDNA are promising noninvasive biomarkers for NPC, offering high sensitivity and specificity, particularly for early-stage and EBV-negative NPC.