Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles.

Zi-Sen ZhangYi-Yan LiuShuang-Shuang HeDai-Qin BaoHong-Chen WangJie ZhangXiao-Yong PengJia-Tao ZangYu ZhuYue WuQing-Hui LiTao LiLiang-Ming Liu

Published in: Military Medical Research (2023)

Pericytes are protective against sepsis through regulating vascular reactivity and barrier function. Possible mechanisms include both direct colonization of microvasculature and secretion of PCMVs.

Keyphrases

septic shock
acute kidney injury
intensive care unit
high glucose
diabetic rats
type diabetes
high fat diet induced
drug induced
metabolic syndrome