Epigenetic restoration and activation of ERβ: an inspiring approach for treatment of triple-negative breast cancer.

Ahmad SalahuddinHeba GhanemGamal A OmranMaged Wasfy Helmy

Published in: Medical oncology (Northwood, London, England) (2022)

The antiproliferative effect of ERβ could be retained when co-expressed with Erα using a powerful epigenetic combination of Decitabine and vorinostat with DPN.

Keyphrases

endoplasmic reticulum
estrogen receptor
dna methylation
breast cancer cells
gene expression
acute myeloid leukemia
combination therapy
replacement therapy
smoking cessation