Metal-free nucleophilic trifluoromethylselenolation via an iodide-mediated umpolung reactivity of trifluoromethylselenotoluenesulfonate.
Kevin GrollierAlexis TaponardArnaud De Zordo-BanliatEmmanuel MagnierThierry BillardPublished in: Beilstein journal of organic chemistry (2020)
We report herein a practical method to generate CF3Se- (and RFSe-) anions from shelf-stable reagents under iodide activation. Metal-free nucleophilic trifluoromethylselenolations have been then performed with this in situ-generated anion. Perfluoroalkylselenolations have also been described.
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