Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
MeiLan K HanWen YeDi WangEmily WhiteMehrdad ArjomandiIgor Z BarjaktarevicStacey-Ann BrownRussell G BuhrAlejandro P ComellasChristopher B CooperGerard J CrinerMark T DransfieldFrank DrescherRodney J FolzNadia N HanselRavi KalhanRobert J KanerRichard E KannerJerry A KrishnanStephen C LazarusVeeranna MaddipatiFernando J MartinezAnne MathewsCatherine MeldrumCharlene McEvoyToru NyunoyaLinda RogersWilliam W StringerChristine H WendtRobert A WiseStephen R WisniewskiFrank C SciurbaPrescott G Woodruffnull nullPublished in: The New England journal of medicine (2022)
Inhaled dual bronchodilator therapy did not decrease respiratory symptoms in symptomatic, tobacco-exposed persons with preserved lung function as assessed by spirometry. (Funded by the National Heart, Lung, and Blood Institute and others; RETHINC ClinicalTrials.gov number, NCT02867761.).