Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T Cells Regresses Refractory Solid Tumors.
Qian LuoJohn V NapoleonXin LiuBoning ZhangSuilan ZhengPhilip S LowPublished in: Molecular cancer research : MCR (2022)
A novel strategy for rejuvenating exhausted CAR-T cells is described previously that promotes downregulation of exhaustion markers and renewed eradication of cancer cells in a tumor mass.