Antimicrobial and immunomodulatory in vitro profile of double antibiotic paste.

Maurício Gonçalves da Costa SousaPatrícia Diniz XavierAna Paula de Castro CantuáriaIngrid Aquino AmorimJeeser Alves AlmeidaOctávio Luiz Franco Taia Maria Berto Rezende

Published in: International endodontic journal (2021)

Double antibiotic paste and TAP had similar antimicrobial activity against S. aureus and E. faecalis. DAP upregulated pro-inflammatory cytokines mainly in the absence of antigens and had pro- and anti-inflammatory activity in RAW 264.7 macrophages and L929 fibroblasts in the presence of antigens involved in pulp infections.

Keyphrases

anti inflammatory
dendritic cells
staphylococcus aureus
molecularly imprinted
extracellular matrix
tandem mass spectrometry