The role of sodium channels in sudden unexpected death in pediatrics.

Anne Maria RochtusRichard D GoldsteinIngrid A HolmCatherine A BrownsteinEduardo Pérez-PalmaRobin HaynesDennis LalAnnapurna H Poduri

Published in: Molecular genetics & genomic medicine (2020)

We report variants in several VGSC genes in cases with SUDP, involving both arrhythmia- and epilepsy-associated genes. Accurate variant assessment as well as future studies are essential for an improved understanding of the contribution of sodium channel-related variants to SUDP.

Keyphrases

copy number
genome wide
bioinformatics analysis
genome wide identification
high resolution
dna methylation
genome wide analysis
current status
gene expression
mass spectrometry