Sputum Gene Expression Reveals Dysregulation of Mast Cells and Basophils in Eosinophilic COPD.
Natasha A WinterPeter G GibsonVanessa Marie McDonaldMichael FrickerPublished in: International journal of chronic obstructive pulmonary disease (2021)
We demonstrate associations of MCs and basophils with eosinophilic inflammation and lower lung function in COPD. These findings are consistent with prior results in asthma and may represent a new tool for endotyping eosinophilic-COPD.