Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0.

Jieyu ZhaoEugene Yui-Ching ChowPui Yan YeungQiangfeng Cliff ZhangTing-Fung ChanChun Kit Kwok

Published in: BMC biology (2022)

rG4-seq 2.0 can improve the identification and study of rG4s in low abundance transcripts, and our findings can provide insights to optimize cDNA library preparation in other related methods.

Keyphrases

single cell
rna seq
genome wide
gene expression
dna methylation
nucleic acid
antibiotic resistance genes
microbial community
mass spectrometry