Microenvironmental Modulation of Calcium Wave Propagation Velocity in Engineered Cardiac Tissues.

Andrew P PetersenDavi M Lyra-LeiteNethika R AriyasingheNathan ChoCeleste M GoodwinJoon Young KimMegan L Rexius-Hall

Published in: Cellular and molecular bioengineering (2018)

Propagation velocity in engineered cardiac tissues is sensitive to features in the tissue microenvironment, such as alignment, matrix elasticity, and matrix topography, which may underlie arrhythmias in conditions with pathological tissue remodeling.

Keyphrases

left ventricular
gene expression
stem cells