Baicalin and baicalein from Scutellaria baicalensis Georgi alleviate aberrant neuronal suppression mediated by GABA from reactive astrocytes.
Juyeong ChoEun-Bin HongYoung-Sik KimJungbin SongYeon Ha JuHyunjin KimHyowon LeeHocheol KimMin-Ho NamPublished in: CNS neuroscience & therapeutics (2024)
In summary, baicalin and baicalein isolated from S. baicalensis reduce astrocyte reactivity and alleviate aberrant tonic inhibition of hippocampal neurons during neuroinflammation.