Peptide-mediated Aqueous Synthesis of NIR-II Emitting Ag 2 S Quantum Dots for Rapid Photocatalytic Bacteria Disinfection.
Peiqing SunKunlun LiXiao LiuJing WangXusheng QiuWei WeiJing ZhaoPublished in: Angewandte Chemie (International ed. in English) (2023)
Pathogenic microorganisms in the environment are a great threat to global human health. The development of disinfection method with rapid and effective antibacterial properties is urgently needed. In this study, a biomimetic silver binding peptide AgBP2 was introduced to develop a facile synthesis of biocompatible Ag 2 S quantum dots (QDs). The AgBP2 capped Ag 2 S QDs exhibited excellent fluorescent emission in the second near-infrared (NIR-II) window, with physical stability and photostability in the aqueous phase. Under 808 nm NIR laser irradiation, AgBP2-Ag 2 S QDs can serve not only as a photothermal agent to realize NIR photothermal conversion but also as a photocatalyst to generate reactive oxygen species (ROS). The obtained AgBP2-Ag 2 S QDs achieved a highly effective disinfection efficacy of 99.06 % against Escherichia coli within 25 min of NIR irradiation, which was ascribed to the synergistic effects of photogenerated ROS during photocatalysis and hyperthermia. Our work demonstrated a promising strategy for efficient bacterial disinfection.
Keyphrases
- quantum dots
- photodynamic therapy
- drug release
- drinking water
- reactive oxygen species
- visible light
- fluorescence imaging
- human health
- sensitive detection
- drug delivery
- fluorescent probe
- escherichia coli
- risk assessment
- energy transfer
- cancer therapy
- dna damage
- cell death
- ionic liquid
- highly efficient
- mental health
- gold nanoparticles
- climate change
- living cells
- loop mediated isothermal amplification
- physical activity
- radiation therapy
- staphylococcus aureus
- transcription factor
- oxidative stress
- high speed
- dna binding