Application of glutamate weighted CEST in brain imaging of nicotine dependent participants in vivo at 7T.

Paul S JacobsJoelle JeeLiu FangEmily DevlinClaudia IannelliDeepa ThakuriJames LougheadCynthia Neill EppersonNeil WilsonDavid RoalfRavinder ReddyRavi Prakash Reddy Nanga

Published in: PloS one (2024)

Feasibility of GluCEST imaging was demonstrated for in vivo investigation of smokers and non-smokers to assess glutamate contrast differences as a potential biomarker with a moderate negative age correlation in the cingulate gyrus suggesting reward network involvement.

Keyphrases

smoking cessation
high resolution
magnetic resonance
resting state
functional connectivity
fluorescence imaging
multiple sclerosis
blood brain barrier
prefrontal cortex