GDF15 predict platinum response during first-line chemotherapy and can act as a complementary diagnostic serum biomarker with CA125 in epithelial ovarian cancer.

Published in: BMC cancer (2018)

Our results provide valuable evidence that GDF15 is related with first-line chemo-resistance, with highly expressed GDF15 being a strong and an independent indicator of shorter PFS in EOC patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
photodynamic therapy
squamous cell carcinoma
patient reported outcomes
combination therapy