Long-Term Metabolic Dysfunction Programming in Female Mice by Serial Moderate Restriction of High Fat High Sucrose Diet.
Micah P WildesDeemantha G FernandoConnie C GrobeJohn J RehoJustin L GrobeSrividya KidambiTammy L KindelAnne E KwitekJeffrey L SegarJoni S WilliamsLisa L MorselliPublished in: Endocrinology (2024)
Our findings suggest that repeated intermittent food restriction leads to changes in eating behavior that predispose to glucose intolerance when food is freely available. Future studies are needed to elucidate the specific mechanisms underlying these changes.