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MicroRNA Regulation for Inflammasomes in High Glucose-Treated ARPE-19 Cells.

Ji Hong KimHyo Seon YuJi Hye KangEun Hee HongMin Ho KangMincheol SeongHeeyoon ChoYong Un Shin
Published in: Journal of ophthalmology (2024)
This study investigated the relationship between miRNAs and inflammasomes in diabetes-induced cells using high glucose-treated ARPE-19 cells. These findings suggested that miR-17 suppresses inflammasomes, thereby reducing the subsequent inflammatory response and indicating that miRNAs and inflammasomes could serve as new therapeutic targets for DR.
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