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A naturalistic effectiveness study of maintenance therapies for the bipolar disorders.

Michael J SpoelmaJoanne LeidreiterAdam BayesArtin JebejianGordon B Parker
Published in: Acta psychiatrica Scandinavica (2023)
This study clearly established a preference for lamotrigine in the maintenance treatment of BP-II. While the literature consistently emphasises the primacy of lithium in bipolar disorder treatment, its side effect profile as observed in this study remains a concern. Future research considering moderators of treatment response and concomitant medications could help to identify further nuances to consider for treatment decision-making.
Keyphrases
  • bipolar disorder
  • systematic review
  • major depressive disorder
  • combination therapy