Interleukin-18 and interferon-γ single nucleotide polymorphisms in Egyptian patients with tuberculosis.

Noha Anwar HassunaMohamed El FekyAliae A R Mohamed HusseinManal A MahmoudNaglaa K IdrissSayed F AbdelwahabMaggie A Ibrahim

Published in: PloS one (2021)

These findings suggest; for the first time in Egypt; a significant risk to TB infection with SNP at the IL-18-137G/C with no LD with SNP at the IL-18-607 site. The homozygous AA genotype in INF-γ+874 showed a significant higher risk to TB than the homozygous TT or heterozygous AT genotypes.

Keyphrases

mycobacterium tuberculosis
genome wide
dendritic cells
emergency department
gene expression
dna methylation
hiv aids
electronic health record