Assessment of stained direct cytology smears of breast cancer for whole transcriptome and targeted messenger RNA sequencing.

Michał MarczykChunxiao FuRosanna LauLili DuAlexander J TrevartonBruno V SinnRebekah E GouldLajos PusztaiChristos HatzisWilliam Fraser Symmans

Published in: Cancer cytopathology (2023)

RNA can be reliably extracted from cytology smears and is suitable for transcriptome profiling or mutation detection, except for signatures of tumor stroma.

Keyphrases

single cell
rna seq
fine needle aspiration
high grade
genome wide
ultrasound guided
gene expression
cancer therapy
loop mediated isothermal amplification
dna methylation
real time pcr