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Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer.

Mingjie AnHanhao ZhengJian HuangYan LinYuming LuoYao KongMingrui PangDingwen ZhangJiabin YangJiancheng ChenYuanlong LiChanghao ChenTianxin Lin
Published in: Cancer research (2022)
This study identifies the novel intron-retained circNCOR1 and elucidates a SUMOylation-mediated DDX39B-circNCOR1-SMAD7 axis that regulates lymph node metastasis of bladder cancer.
Keyphrases
  • lymph node metastasis
  • squamous cell carcinoma
  • papillary thyroid
  • epithelial mesenchymal transition
  • transforming growth factor
  • genome wide