Enhanced IL-37-IL-1R8 axis is negatively associated with inflammatory and clinical severity of chronic rhinosinusitis with nasal polyps.

Jia ZhangYujie CaoKun ChenXianting HuChun ZhouLei LiMiaomiao HanDehui WangHuabin Li

Published in: Asia Pacific allergy (2024)

Our findings showed that enhanced IL-37-IL-1R8 axis in NP tissues was negatively associated with inflammatory and clinical severity of CRSwNP patients, which could be considered as a future therapeutic target in CRSwNP patients.

Keyphrases

chronic rhinosinusitis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
oxidative stress
gene expression
prognostic factors
patient reported
current status