A non-invasive 25-Gene PLNM-Score urine test for detection of prostate cancer pelvic lymph node metastasis.
Jinan GuoLiangyou GuHeather JohnsonDi GuZhenquan LuBinfeng LuoQian YuanXuhui ZhangTaolin XiaQingsong ZengAlan H B WuAllan JohnsonNishtman DizeyiPer-Anders AbrahamssonHeqiu ZhangLingwu ChenKefeng XiaoChang ZouJenny L PerssonPublished in: Prostate cancer and prostatic diseases (2024)
The novel 25 G PLNM-Score is the first highly accurate and non-invasive machine learning algorithm-based urine test to identify PLNM before PLND, with potential clinical benefits of avoiding unnecessary PLND and improving treatment decision-making.
Keyphrases
- lymph node metastasis
- machine learning
- prostate cancer
- decision making
- squamous cell carcinoma
- papillary thyroid
- radical prostatectomy
- deep learning
- artificial intelligence
- rectal cancer
- genome wide
- high resolution
- copy number
- big data
- loop mediated isothermal amplification
- genome wide identification
- human health
- real time pcr
- climate change
- risk assessment
- combination therapy
- replacement therapy