Monocyte and neutrophil levels are potentially linked to progression to IPF for patients with indeterminate UIP CT pattern.

Andrew AchaiahAmila RathnapalaAndrea PereiraHarriet BothwellKritica DwivediRosie BarkerRachel BenamoreRachel K HoylesValentina IotchkovaLing-Pei Ho

Published in: BMJ open respiratory research (2021)

53% of our evaluable patients with iUIP progressed to IPF over a mean of 4 years. Monocyte and neutrophil levels at initial CT were significantly associated with progression in disease. These data provide a single-centre analysis of the evolution of patients with iUIP CT pattern, and first signal for potential factors associated with progression to IPF.

Keyphrases

idiopathic pulmonary fibrosis
image quality
dual energy
computed tomography
contrast enhanced
dendritic cells
positron emission tomography
magnetic resonance imaging
endothelial cells
peripheral blood
electronic health record
magnetic resonance
big data
climate change
deep learning
human health
data analysis