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Can a sperm selection technique improve embryo ploidy?

Olena M KocurPhilip XieStephanie CheungSydney SounessMary McKnightZev RosenwaksGianpiero D Palermo
Published in: Andrology (2022)
In couples with a relatively young female partner with a negative infertility work-up, and a male partner with semen parameters adequate for ICSI presenting with a high rate of embryo aneuploidy, an additional subtle male factor component may be the culprit. Thus, it is crucial to assess the SCF and test for the dsDNA breaks, which can eventually contribute to embryo chromosomal abnormalities. Given the inverse relationship between SCF and motility, selection of the most motile gamete by MFSS enhanced the proportion of spermatozoa with an intact genome contributing to the generation of more euploid embryos that are capable of implanting and yielding higher term pregnancies. This article is protected by copyright. All rights reserved.
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