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Exercise Training Protects Against Heart Failure Via Expansion of Myeloid-Derived Suppressor Cells Through Regulating IL-10/STAT3/S100A9 Pathway.

Lifeng FengGuangru LiJiale AnChang LiuXiaolong ZhuYang XuYang GaoJing LiJie LiuJie YanYachen WangJiling RenGuangru LiZhi Qi
Published in: Circulation. Heart failure (2021)
ET could increase MDSCs by stimulating the secretion of IL-10 from macrophage, which was through IL-10/STAT3/S100A9 signaling pathway, thereby achieving the role of heart protection.
Keyphrases
  • heart failure
  • signaling pathway
  • induced apoptosis
  • cell proliferation
  • cell cycle arrest
  • pi k akt
  • skeletal muscle
  • adipose tissue
  • atrial fibrillation
  • acute heart failure