Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation.

Jing MaYi-Hui HouZhe-Yan LiaoZheng MaXiao-Xuan ZhangJian-Li WangYun-Bo ZhuHai-Lei ShanPing-Yue WangCheng-Bo LiYing-Lei LvYi-Lan WeiJie-Zhi Dou

Published in: Degenerative neurological and neuromuscular disease (2023)

Leptin signaling would regulate the activation of microglia and the release of inflammatory factors, but it is not the only underlying mechanism in the neuroprotective effects of AD pathogenesis.

Keyphrases

mouse model
inflammatory response
lipopolysaccharide induced
lps induced
cerebral ischemia
neuropathic pain
traumatic brain injury
cognitive decline
oxidative stress
subarachnoid hemorrhage
blood brain barrier
mild cognitive impairment