Persistent Autoimmune Activation and Proinflammatory State in Post-Coronavirus Disease 2019 Syndrome.

Yeny Acosta-AmpudiaDiana M MonsalveManuel Eduardo Rojas-QuintanaYhojan RodríguezElizabeth ZapataCarolina Ramírez-SantanaJuan-Manuel Anaya

Published in: The Journal of infectious diseases (2022)

The clinical manifestations of PCS are associated with the persistence of a proinflammatory and effector phenotype induced by SARS-CoV-2 infection. This long-term persistent immune activation may contribute to the development of latent and overt autoimmunity. Results suggest the need to evaluate the role of immunomodulation in the treatment of PCS.

Keyphrases

coronavirus disease
respiratory syndrome coronavirus
dendritic cells
case report
sars cov
immune response
combination therapy
drug induced