Platelet Membrane-Coated Nanoparticles Target Sclerotic Aortic Valves in ApoE-/- Mice by Multiple Binding Mechanisms Under Pathological Shear Stress.
Hongbo YangYanan SongJing ChenZhiqing PangNing ZhangJiatian CaoQiaozi WangQiyu LiFeng ZhangYuxiang DaiChenguang LiZheyong HuangJuying QianJunbo GePublished in: International journal of nanomedicine (2020)
PNPs could provide a promising platform for the molecular diagnosis and targeting treatment of aortic valve disease.
Keyphrases
- aortic valve
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- aortic stenosis
- high throughput
- cancer therapy
- type diabetes
- heart failure
- metabolic syndrome
- coronary artery disease
- combination therapy
- dna binding
- insulin resistance
- left ventricular
- transcription factor