Serum alanine aminotransferase level and liver-related mortality in patients with chronic hepatitis B: A large national cohort study.
Jae-Jun ShimJung Wook KimChi Hyuk OhYe-Rin LeeJi Sung LeeSo-Youn ParkByung-Ho KimIn-Hwan OhPublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
The liver-related mortality rate increased significantly, even in CHB patients with relatively low serum ALT levels. Careful monitoring or earlier antiviral therapy should be considered for patients aged >40 years with serum ALT levels above the upper limit of normal.