Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization.

R David AndrewEszter FarkasJed A HartingsK C BrennanOscar HerrerasMichael MüllerSergei A KirovCenk AyataNikita Ollen-BittleClemens ReiffurthOmer RevahR Meldrum RobertsonKen D Dawson-ScullyGhanim UllahJens P Dreier

Published in: Neurocritical care (2022)

Spreading depolarizations better account for the acute neuronal injury arising from brain ischemia than does the early and excessive release of glutamate.

Keyphrases

liver failure
respiratory failure
resting state
white matter
cerebral ischemia
aortic dissection
drug induced
functional connectivity
oxidative stress
weight gain
multiple sclerosis
brain injury
intensive care unit
subarachnoid hemorrhage