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Development of Phenotyping Algorithms for the Identification of Organ Transplant Recipients: Cohort Study.

Lee WhelessLaura X BakerLaVar D EdwardsNimay AnandKelly A BirdwellAllison HanlonMary-Margaret Chren
Published in: JMIR medical informatics (2020)
Electronic health records linked to biobanks are increasingly used to conduct large-scale studies but have not been well-utilized in organ transplantation research. We present rigorously evaluated methods for phenotyping OTRs from electronic health records that will enable the use of the full spectrum of clinical data in transplant research. Using several different machine learning algorithms, we were able to identify transplant cases with high accuracy by using only ICD and CPT codes.
Keyphrases
  • electronic health record
  • machine learning
  • high throughput
  • clinical decision support
  • artificial intelligence
  • big data
  • deep learning
  • adverse drug
  • case control
  • cell therapy
  • bioinformatics analysis