Regional, not global, functional connectivity contributes to isolated focal dystonia.

Scott A Norris Aimee E Morris Meghan C CampbellMorvarid KarimiBabatunde AdeyemoRandal C Paniello Abraham Z Snyder Steven E Petersen Jonathan W Mink Joel S Perlmutter

Published in: Neurology (2020)

Regional functional connectivity differences, not global network level dysfunction, contributes to common pathophysiologic mechanisms in isolated focal dystonia. Rigorous quality control eliminated spurious large-scale network differences between patients with focal dystonia and control participants.

Keyphrases

functional connectivity
resting state
deep brain stimulation
quality control
early onset
oxidative stress