Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes.
Felicity NewellPeter A JohanssonJames S WilmottKatia NonesVanessa LakisAntonia L PritchardSerigne N LôRobert V RawsonStephen H KazakoffAndrew J ColebatchLambros T KoufariotisPeter M FergusonScott WoodConrad LeonardMatthew H LawKelly M BrooksNatasa BroitJane M PalmerKasey L CoutsIsmael A VergaraGeorgina V LongAndrew P BarbourOmgo E NiewegBrindha ShivalingamWilliam A RobinsonJonathan R StretchAndrew J SpillaneRobyn P M SawKerwin F ShannonJohn F ThompsonGraham J MannJohn V PearsonRichard A ScolyerNicola WaddellNicholas K HaywardPublished in: Cancer discovery (2022)
This is the largest whole-genome analysis of melanoma to date, comprehensively comparing the genomics of the four major melanoma subtypes. This study highlights both similarities and differences between the subtypes, providing insights into the etiology and biology of melanoma. This article is highlighted in the In This Issue feature, p. 2711.