Correlation Analysis between the Viral Load and the Progression of COVID-19.
Wenyu ChenQinfeng XiaoZhixian FangXiaodong LvMing YaoMin DengPublished in: Computational and mathematical methods in medicine (2021)
The results of this study demonstrated that viral load of SARS-CoV-2 is significantly negatively correlated with lymphocyte count, but markedly positively correlated with neutrophil count and CRP. The rise of viral load is very likely to be the key factor leading to the overloading of the body's immune response and resulting in the disease progression into severe disease.