Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer.

Alexandra CanoniciAlacoque L BrowneMohamed F K IbrahimKevin P FanningSandra RocheNeil T ConlonFiona O'NeillJustine MeillerMattia CremonaClare MorganBryan T HennessyAlexander J EustaceFlavio SolcaNorma O'DonovanJohn Crown

Published in: Therapeutic advances in medical oncology (2020)

We demonstrate that afatinib combined with dasatinib has potential clinical activity in TNBC but warrants further preclinical investigation.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
small cell lung cancer
human health
cancer therapy
risk assessment
advanced non small cell lung cancer
cell therapy
bone marrow
replacement therapy
chronic myeloid leukemia