Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.

Jianan WangJiayu LiuJinyang WangShijian WangFeifei LiRuibing LiPeng LiuMianyang LiChengbin Wang

Published in: Cancer cell international (2022)

HSPA4, SPTB and NIPSNAP1 in tumor biopsies and/or their optional combinations might be potential predictive markers for nCRT response in patients with LARC. The DEPs and their related functions have implications for the potential mechanisms of treatment response to nCRT in patients with LARC.

Keyphrases

rectal cancer
locally advanced
neoadjuvant chemotherapy
phase ii study
squamous cell carcinoma
end stage renal disease
radiation therapy
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
lymph node
ultrasound guided
patient reported outcomes
study protocol
patient reported