Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study.
Xianyong YinKwangwoo KimHiroyuki SuetsuguSo-Young BangLeilei WenMasaru KoidoEunji HaLu LiuYuma SakamotoSungsin JoRui-Xue LengNao OtomoYoung-Chang KwonYujun ShengNobuhiko SuganoMi Yeong HwangWeiran LiMasaya MukaiKyungheon YoonMinglong CaiKazuyoshi IshigakiWon Tae ChungHe HuangDaisuke TakahashiShin-Seok LeeMengwei WangKohei KarinoSeung-Cheol ShimXiaodong ZhengTomoya MiyamuraYoung Mo KangDong-Qing YeJunichi NakamuraChang-Hee SuhYuanjia TangGoro MotomuraYong-Beom ParkHuihua DingTakeshi KurodaJung-Yoon ChoeChengxu LiHiroaki NiiroYoungho ParkChangbing ShenTakeshi MiyamotoGa-Young AhnWenmin FeiTsutomu TakeuchiJung-Min ShinKeke LiYasushi KawaguchiYeon-Kyung LeeYong-Fei WangKoichi AmanoDae Jin ParkWanling YangYoshifumi TadaYu Lung LauKen YamajiZhengwei ZhuMasato ShimizuTakashi AtsumiAkari SuzukiTakayuki SumidaYukinori OkadaKoichi MatsudaKeitaro MatsuoYuta Kochinull nullKazuhiko YamamotoKoichiro OhmuraTae Hwan KimSen YangTakuaki YamamotoBong-Jo KimNan ShenShiro IkegawaHye-Soon LeeXuejun ZhangChikashi C TeraoYong CuiSang-Cheol BaePublished in: Annals of the rheumatic diseases (2022)
Cell-level TWAS in six types of immune cells complemented SLE gene discovery and guided the identification of novel genetic associations. The gene findings shed biological insights into SLE genetic associations.