Association of autoantibody levels with different stages of age-related macular degeneration (AMD): Results from the population-based Gutenberg Health Study (GHS).
Christina A KorbKarl J LacknerDominik WoltersAlexander K SchusterStefan NickelsVanessa M BeutgenThomas MünzelPhilipp S WildManfred E BeutelIrene SchmidtmannNorbert PfeifferFranz H GrusPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2023)
This study contributes to a growing knowledge of autoantibodies in association with different AMD stages compared to controls in the context of a large population-based study in Germany. Especially autoantibodies against inflammatory proteins were downregulated in participants with early AMD and soft, distinct drusen (≥63 μm) or pigmentary abnormalities only.