The role of vascular dementia associated genes in patients with Alzheimer's disease: A large case-control study in the Chinese population.

Xuewen XiaoLina GuoXinxin LiaoYafang ZhouWeiwei ZhangLu ZhouXin WangXixi LiuHui LiuTianyan XuYuan ZhuQijie YangXiaoli HaoYingzi LiuJun-Ling WangJinchen LiBin JiaoLu Shen

Published in: CNS neuroscience & therapeutics (2021)

Common variants in COL4A1 and rare variants in HTRA1, NOTCH3, COL4A1, and CST3 may be implicated in AD pathogenesis. Besides, GSN, ITM2B, and COL4A1 are probably involved in the development of AD endophenotypes.

Keyphrases

copy number
mild cognitive impairment
cognitive decline
gene expression
genome wide identification