Interleukin-18 in patients with acute coronary syndromes.
Axel ÅkerblomStefan K JamesTatevik G LakicRichard C BeckerChristopher P CannonPhillippe Gabriel StegAnders HimmelmannHugo A KatusRobert F StoreyLars WallentinW Douglas WeaverAgneta Siegbahnnull nullPublished in: Clinical cardiology (2019)
In ACS patients, IL-18 concentrations increased after the acute event and remained increased for 6 months. Baseline IL-18 levels were significantly associated with CV mortality, independent of clinical characteristics and indicators of renal/cardiac dysfunction but this association was attenuated after adjustment for multiple biomarkers.
Keyphrases
- acute coronary syndrome
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- liver failure
- prognostic factors
- peritoneal dialysis
- oxidative stress
- left ventricular
- heart failure
- percutaneous coronary intervention
- type diabetes
- cardiovascular disease
- coronary artery disease
- patient reported outcomes
- hepatitis b virus
- atrial fibrillation
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- mechanical ventilation