The Krüppel-like factor (KLF5) as a predictive biomarker in preoperative chemoradiation therapy for rectal cancer.

Jeong Yeon KimSung Gil ParkKyung-Sub KimYong Hee ChoiNam Kyu Kim

Published in: Annals of surgical treatment and research (2019)

KLF5 was significantly associated with the presence of KRAS mutations, and KLF5 was an independent poor response predictor of CRT in rectal cancer. Our study is pilot study and more research will be needed in the future.

Keyphrases

rectal cancer
locally advanced
transcription factor
patients undergoing
squamous cell carcinoma
radiation therapy
current status
wild type