Lack of Causal Effects or Genetic Correlation between Restless Legs Syndrome and Parkinson's Disease.

Mehrdad A EstiarKonstantin SenkevichEric YuParizad VarghaeiLynne KrohnSara Bandres-CigaAlastair J Noyce Guy A Rouleau Ziv Gan Or

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

There was no evidence for a causal relationship or genetic correlation between restless legs syndrome and PD. The associations observed in epidemiological studies could be attributed, in part, to confounding or nongenetic determinants. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

genome wide
case report
copy number
gene expression
case control
dna methylation