Atomically Thin TaSe 2 Film as a High-Performance Substrate for Surface-Enhanced Raman Scattering.
Yuancai GeFei WangYing YangYi XuYing YeYu CaiQingwen ZhangShengying CaiDanFeng JiangXiaohu LiuBo LiedbergJian MaoYi WangPublished in: Small (Weinheim an der Bergstrasse, Germany) (2022)
An atomically thin TaSe 2 sample, approximately containing two to three layers of TaSe 2 nanosheets with a diameter of 2.5 cm is prepared here for the first time and applied on the detection of various Raman-active molecules. It achieves a limit of detection of 10 -10 m for rhodamine 6G molecules. The excellent surface-enhanced Raman scattering (SERS) performance and underlying mechanism of TaSe 2 are revealed using spectrum analysis and density functional theory. The large adsorption energy and the abundance of filled electrons close to the Fermi level are found to play important roles in the chemical enhancement mechanism. Moreover, the TaSe 2 film enables highly sensitive detection of bilirubin in serum and urine samples, highlighting the potential of using 2D SERS substrates for applications in clinical diagnosis, for example, in the diagnosis of jaundice caused by excess bilirubin in newborn children.
Keyphrases
- sensitive detection
- loop mediated isothermal amplification
- density functional theory
- quantum dots
- label free
- reduced graphene oxide
- gold nanoparticles
- molecular dynamics
- room temperature
- young adults
- real time pcr
- raman spectroscopy
- single cell
- risk assessment
- antibiotic resistance genes
- fluorescent probe
- microbial community
- data analysis
- transition metal