Altered anal slow-wave pressure activity in low anterior resection syndrome: short case series in two independent specialist centres provide new mechanistic insights.
Paul F VollebregtLukasz WiklendtDaphne AngMary L VennMira MekhaelPeter ChristensenPhil G DinningCharles H KnowlesS Mark ScottPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)
Over half of the male LARS patients studied had altered anal slow-wave pressure activity based on analysis of HR-ARM recordings. Further studies could investigate the relative contributions of sex, human baseline variance and neoadjuvant/surgical therapies on anal slow waves, and correlate the presence of abnormal activity with symptom severity.