The role of adjuvant chemotherapy in patients with H3K27 altered diffuse midline gliomas: a multicentric retrospective study.

Vincenzo Di NunnoGiuseppe LombardiMatteo SimonelliGiuseppe MinnitiAngela MastronuzziValentina Di RuscioMartina CorràMarta PadovanMarta MaccariMario CacceseGiorgia SimonettiArianna BerlendisMariangela FarinottiBianca PolloManila AntonelliAntonio Di MuzioAngelo DipasqualeSofia AsioliDario De BiaseAlicia TosoniAntonio SilvaniEnrico Franceschi

Published in: Journal of neuro-oncology (2024)

In our series, adjuvant treatment after radiotherapy can be useful in improving OS of patients with H3K27-altered DMG. When feasible another systemic treatment after treatment progression could be proposed.

Keyphrases

early stage
radiation therapy
squamous cell carcinoma
low grade
locally advanced
replacement therapy