Aggregation, segregation, and dispersal of homotypic germ plasm RNPs in the early zebrafish embryo.

Celeste C Eno Christina L Hansen Francisco Pelegri

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

Our findings suggest that germ plasm aggregates act as subcellular compartments that temporarily collect and carry single RNA-type RNPs from fertilization until their cytoplasmic dispersal in PGCs at the end of the blastula period, and describe a previously unknown fragmentation step that allows for an increase in the pool of germ plasm-carrying cells, presumably PGCs. Developmental Dynamics 248:306-318, 2019. © 2019 Wiley Periodicals, Inc.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
cell death
signaling pathway