One-Year Follow-Up of Subthalamic Nucleus Deep Brain Stimulation in SNCA Mutation Parkinsonism: A Case Report.

Eve Fouarge Gaëtan GarrauxBruno KaschtenAnne-Laure SaladoEric Parmentier

Published in: Tremor and other hyperkinetic movements (New York, N.Y.) (2023)

This is a case report of a patient with genetic parkinsonism due to SNCA duplication undergoing bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. The outcome was favorable one year after implantation, with the patient coming off all anti-Parkinson's medications. This further clarifies DBS outcome in monogenic Parkinson's disease.

Keyphrases

deep brain stimulation
parkinson disease
obsessive compulsive disorder
case report
minimally invasive
genome wide
drug induced
gene expression
dna methylation
copy number
percutaneous coronary intervention