Almost 10 years of PET/MR attenuation correction: the effect on lesion quantification with PSMA: clinical evaluation on 200 prostate cancer patients.
Borjana BogdanovicAndrei GafitaSylvia SchachoffMatthias EiberJorge CabelloWolfgang A WeberStephan G NekollaPublished in: European journal of nuclear medicine and molecular imaging (2020)
Based on these results and the encountered bone atlas registration inaccuracy, we deduce that including bones and extending the MR field-of-view did not introduce clinically significant differences in PSMA diagnostic accuracy and tracer uptake quantification in prostate cancer pelvic lesions, facilitating the analysis of serial studies respectively. However, in the absence of ground truth data, we advise against atlas-based methods when comparing serial scans for bone lesions.
Keyphrases
- prostate cancer
- pet ct
- pet imaging
- clinical evaluation
- contrast enhanced
- positron emission tomography
- bone mineral density
- computed tomography
- single cell
- radical prostatectomy
- magnetic resonance
- bone loss
- bone regeneration
- soft tissue
- postmenopausal women
- electronic health record
- big data
- rectal cancer
- magnetic resonance imaging
- machine learning
- case control
- benign prostatic hyperplasia